Field of Science

Showing posts with label chat. Show all posts
Showing posts with label chat. Show all posts

Who's Afraid of the Wasabi Fire Alarm ?

It was a strange series of events that lead me to having dinner with IgNobel awards maestro Marc Abrahams, former Monty Python Terry Jones and the inventors of the wasabi fire alarm. I had met Marc at the IgNobel show when it came to Imperial. I know I should have been writing up my PhD, but  one night surely wouldn't matter too much ?
 We ended up talking about this new fire alarm that had been invented by a couple of japanese researchers. This fire alarm was not like normal ones. Instead of ringing, it sprayed an infusion of wasabi into the air. Who could possible want a fire alarm that sprays you with wasabi. Isn't it bad enough being inside a burning building, and now they've invented a fire alarm and burns you from the inside too ?
This product was marketed to the deaf, which to me suggested a new horror was being inflicted on the disabled. I suggested that it would be useful for clearing out rooms in a night club when the music was too loud. Because I don't like nightclubs or the people who use them. So as we talked, Marc mentioned that the two IgNobel prize winners were coming into the country to exhibit their invention, and would I like to come along and discuss my ideas with them.
So that was how I ended up at the Science Museum to meet the inventors of the fire alarm. To my surprise Dr Makoto Imai was a friendly psychiatrist from Sapporo had helped test out the fire alarm, and his somewhat more subdued colleague, Hideako Gotou were not the vindicitive pranksters I had hoped for expected.
They had brought with them their new invention. It was quite simply a fire alarm with a wire attaching it to one of those automatic air fresheners you see in more upmarket public toilets. We were shown into the science museum, which was planning to exhibit the fire alarm. Marc and Steve Colgan  (of colganology) and I were treated to an enthusiastic tour of the museum by former New Scientist editor Roger Highfield. He had taken to the new role with aplomb, positively bouncing with excitement about all of the new exhibits and events happening at the museum.
After this, we ended up taking the inventors to the Knightsbridge fire station for a photo op.
Eventually a Tom Whipple, a journalist from the Times arrived, and displayed true dedication to his profession by making Dr Imai demonstrate the power of the alarm directly.




Immediately after he had finished dousing the choking journalist with wasabi spray, the inventor wryly noted that "This is a misuse of this system".
Whilst the effects are dramatic, and painful, the recovery was rapid.  Tom had to get quite close to the spray to get the worst effects. I was told this system would be mounted in such a way as to avoid situations where users get blasted in the face as demonstrated above.
Since the inventors were only going to be in London for a day, Marc had offered to show them around some of the best tourist attractions. As the Photo Op was drawing to a close, Marc said that he was taking the Inventors to meet Terry Jones at Centre Point, and whether Steve and I would like to come along. Whilst I still had a lot of writing to do for my thesis, I was not going to let it get in the way of meeting one of the Pythons.
So we ended up in a restaurant in one of the tallest buildings in the centre of london. If the day hadn't been so foggy, I would have been able to see my house from it. And so we sat down to dinner with our esteemed host and his wife. Later that day I would go home and be quizzed about the whole experience by my flatmates. They would ask whether he had eaten waffffer thin mints and look eachother knowingly as if this was a reference I should get.  I was spending too much time trying talking to Dr Imai, trying to decipher his motives for creating a wasabi spraying alarm.
  I asked him exactly how did this idea came into being?
 The original idea for the alarm came from the author Karin Matsumori. She had lost her hearing during her time at school, and had intially pitched the idea of an odour based alarm system to the perfume company Seems Inc.
At this point, Dr Imai noticed that I was feverishly writing all of this down on my arm. I had left the house without my note pad. So I had been writing notes on my hand since the museum. By the time we had reached the restaurant, my arm had begun to turn blue.
 Noticing this, He produced a business card, and wrote the pertinent details in neat handwriting. I asked him why the focus of his alarm system was on odour, rather than say, flashing lights.
There were a variety of problems with visual systems. What if the lighting system was not visible from wherever the person was?  And the most pressing concern was how to get someone to wake up quickly in the event of fire.
Conventional Fire alarms rely on triggering the startle reflex. When a human hears a loud unexpected noise, this reflex kicks into action to make you alert to possible danger. It can wake you up out of a deep sleep, and help you escape a fire. To demonstrate the startle response, watch this with the sound off, and then with the sound turned right up.



stereo skifcha from xgabberx on Vimeo.


So visual cues just don't have the same impact. So the question is whether the addition of an olfactory cue would make this type of alarm more effective.But this reflex is based solely on sound. A deaf person cannot react to these cues, so they would not be awakened. So how could they get a fire alarm for the deaf that could wake them out of a deep sleep. The solution was to use a different sense altogether. The sense of smell.
 Seems Inc tried out a number of different fragrances, such as the smell of dirty old socks, and others to see what would work. At some point, they contacted Dr Imai and asked him to conduct a trial with wasabi to see if it could wake people up.
Then  it occurred to me that since Dr Imai was a clinical psychiatrist, there was one key question that I needed to ask. What has this research told him about the brain?
He told me that the way the brain processes the smell of wasabi is quite different to how it treats most other smells. Most of the things you smell are processed by an area of your brain called the olfactory bulb which cuddles up against the back of your nose. When sensory neurones detect smells, they relay this information to the bulb, which can interpret these signals and relay this information to the rest of the brain. Pretty much everything that you can smell goes through this region. However, there is a problem.When you sleep, the olfactory system becomes dormant as well.  This may have been a problem for the inventors of the odour alarm.
But there are certain chemicals which don't limit themselves to using the olfactory system. For instance, when you fry chillis you will no doubt notice that the smell stings the nostrils somewhat. When cutting onions, your eyes will often betray you and start to weep. These are examples of smells which activate pain receptors in mucus membranes in the eyes. When Dr Imai took electro encephalogram readings of the brains of volunteers exposed to wasabi, he noticed this manifest as trigeminal nerve activation.
The trigeminal nerve is not the most famous of the cranial nerves, but it is important. It controls the muscles around the face and mouth, and processes pain in these areas. This is why you get a stinging sensation in addition to flavour when you eat spicy food.
If you happen to be ill, and are bunged up with a stuffy nose, whilst most of the sensory neurones associated with olfaction get knocked out, the trigeminal system is still in working condition. Most importantly, the trigeminal system doesn't go to sleep when you do.  So odours that can have an effect on this system will be able to wake you up from a sleep.
As I noted earlier there are a number of different odours which can activate this system, to different extents.  One viable candidate was capsaicin, the primary component of pepper spray. So why aren't we talking about an alarm that pepper sprays you ? In a word, boiling points.
Capsaicin has a higher boiling point than the odorant in Wasabi. This basically means that unless the fire was already too hot to survive, the fire alarm would have to physically squirt you with the liquid. If you are out of its range, it is pretty much useless.
 The chemical that gives wasabi it's smell however has quite a low boiling point, and exists as a gas. That is why when you have wasabi, it hits you in the nose, whereas a chilli exerts most of its fire in the mouth.
I asked whether this odour could travel faster than say the smell of smoke, and whether it would wake people up before the fire had gotten out of control. The solution here would be to have multiple odour dispensers in a house linked to a smoke detector system, so that no matter where you were, the smell of wasabi would reach you before the smell of smoke.
Is it possible to get used to the smell ? Hypothetically it's possible, if unlikely. Because of the way it acts to elicit pain, it would be harder for people to get used to its smell, in the same way that you can get used to the smell of a fart after a while. However, it's your olfactory system that controls how you adapt to smells, and is the reason why people are mostly unaware of their own body odour. However, the pain sensing system does turn itself off in the same way. However, if people eat enough wasabi on a regular basis , it is possible for them to become less sensitised to the stinging sensation. Of course the only way to test whether this were true would be to find wasabi eating champions, test whether they need more spray to wake them up.
Speaking of which, it turns out that there is someone working on an alarm clock that will sprays wasabi. That's something to look forward to.
But despite my initial skepticism about the practical uses of the wasabi fire alarm, I was slowly won over. These weren't just a pari of eccentric inventors who had decided to add another terror to being trapped in a burning building. They had identified a specific safety concern for the deaf. And to solve this problem, they had come up unique and well thought out solution to this problem.  In spite of myself, I was surprised. While their research had made me laugh, and it was now getting me to think. What else should I have expected from IgNobel prize winners ?

Write Up Mode : Activate !

Use Thundershock you Fool! Books are weak to Electric !

It's over, and I'm overwhelmed. I've finished my last set of experiments. My feelings upon leaving the lab are difficult to sum up. There is so much more I could've done ! If I'd worked smarter, if I'd planned some experiments better, or if I'd gotten luckier. But the lab work had to stop sometime.
It only hit me how much work I still had ahead of me when I packed away all of the various papers, notes and lab diaries that had accumulated on my desk. It all looked fine, neatly packed into a large duffel bag, until I did my back in trying to lift the damned thing. Distilling a thesis from all of that may take up a lot of my time.
I don't know how this will effect my blogging yet. I reckon I can still find the time to do it, considering how I was still able to do it when spending most of my time in the lab, so in theory I should be able to find time to write/ draw for this blog. But I've never written a PhD thesis before so I don't know for sure. I'm toying with the idea of blogging about the thesis writing process as it happens, but I'll have to wait and see.

Review of the Year

The time of the year has arrived, where we all collectively look back, and go, what the hell was that ?
 I remember starting this year, with the absolute certainty that it was going to be terrible. VAT increases, job losses, public service cuts. 2010 was a year of extreme worry.
My Blogger traffic statistics hates 2010 so much that it has been completely expunged from the timeline.

But the traffic statistics also tell another story.
When I started this blog, nearly five years ago, it was purely as a revision aid, to help me set down my thoughts about certain subjects that I was studying. I didn't seek readership, and naturally I didn't get any, Then I started my PhD, and promptly forgot the damn thing existed.
Then in November 2010, I found myself directed to "science of blogging", and once again , enthused, I decided to start a blog. And then I found that Memoirs of a Defective Brain was still here. Everything was just as I left it, even though it had been such a long time. All of the posts that I published, all of the drafts that I intended to publish, but never did. I blew out the cobwebs, tightened up the site design, and started writing posts for research blogging, and for the MolBio carnival.
And something weird happened. People actually started reading. Every spike in my pageview statistics correlated with a spike in dopamine.  Of course finding the time to write the kind of blog posts I wanted was (and still is) time consuming. Nevertheless, when the Blogmaster solicited applications for new bloggers to join field of science, I signed up. Probably one of my best decisions ever.
That big spike in my stats in August came from a collaboration of multiple bloggers, where we each discussed the question "Are we doomed ?", and we got some excellent and creative posts about how dangerous viruses, Uncontrolled populations, Incredible Human Stupidity, and the universe is in general trying to kill us. I drew a silly comic where everyone had funny legs.
And since then , I've managed to keep a minimum of about 1,000 page views per month. My proudest achievement has my series on the history of scarlet fever. These have been in the works for a very long time, with many spare moments reading centuries old papers on scarlet fever and streptococci finally paying off. I learned about characters like Johann Weyer, Daniel Sennert and of course Thomas Sydenham, all of whom were interesting in their own right, and each of whom played a role in the History of Scarlet Fever.
And the process of researching and writing for this weblog has helped me innovate my own research, and those of my colleagues. But that's a story I'd like to tell another day, when I (or my colleagues) publish on it.
But it was not all happiness and blog writing. In the wider world, the year was not always so great.

Greece was caught out on it's tax returns, revealing the fragility of the european constitution, and bringing us to the precipice. We still don't know whether the european single market will collapse, and what effect that will have on the UK, but it's out of our hands, since we vacated our seat at the table.
Riots and protests have erupted worldwide. And when these riots turned up on my doorstep, I was surprised, worried and (shamefully) slightly thrilled.
But that same swell of global anger has shaken the foundations of governments worldwide. The Arab spring is the story of the year, with the Tunisian, Egyptian and Libyan revolutions toppling dictators. And every blow was filmed, tweeted and blogged. The power of protest had been demonstrated, and suddenly others worldwide found their voice. If they weren't happy about the way things were, there was something they could do about it. Suddenly financial centres worldwide began to attract occupiers. The idea of popular revolution, remixed and spread throughout the world.
And this is why I have hope for the next year. As hard as times get, humanities propensity for innovation will prevail. The ability to take one idea, re-assess it, improve it and develop and progress is our greatest strength.
And I can show one event that demonstrated this incredible ingenuity, of people taking one idea, and making it their own.



So what do we expect for 2012 ?

More posts on Scarlet Fever's History. You can look forward to learning about great doctors, like Francis Russell Elkington, and Robert Storr.
More Phylomon ! I have been lacking in inspiration lately, but next year I hope to start drawing more bacteria.
And of course, we can expect the giant space god of the Mayans to come down and say "Hey, you guys need a new calendar ? We heard your last one ran out".
And London 2012 will be so bad that the world will end out of sheer embarrassment.